Office of Technology Commercialization

Innovations: Drug Development Keyword

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Innovation Title Categories Lead Inventor
Small Molecules for Reduction of Fibril Formation in Prone-to-aggregate Protein
2023-FORT-69996
  1. Pharmaceuticals
  2. Biotechnology
Fortin, Jessica
A Fluorescence-based Assay Benefitting PROTAC Drug Discovery and Development
2023-DAS-69989
  1. Pharmaceuticals
  2. Biotechnology
Das, Chittaranjan
Polymer Salts for Improved Drug Delivery from Amorphous Solid Dispersions
2022-TAYL-69671
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Taylor, Lynne S
Folate Receptor-Targeted Conjugates for Treatment of Spinal Trauma
2021-LOW-69272
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Low, Philip Stewart
Highly Potent HIV-1 Protease Inhibitors with Polycyclic-THF Ligands
2020-GHOS-68891
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Ghosh, Arun K
Cancer Combination Therapy with an Immunofunctional Carrier of Drugs and Genes
2021-YEO-69447
  1. Pharmaceuticals
  2. Biotechnology
Yeo, Yoon
Antibiotic Discovery via BICyCLE (Biologically Inspired Chemically Created Leads)
2021-PARK-69383
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Parkinson, Elizabeth Ivy
Novel Approach to Induce Protection Against Respiratory Viruses
2021-MITT-69166
  1. Biotechnology
Mittal, Suresh K
Modified Bis-amide Derivatives as Protease inhibitors for treatment of Covid-19
2021-GHOS-69206
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Ghosh, Arun K
Selective GRK5 Inhibitors for Heart Failure and Cancer
2020-TESM-68925
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Tesmer, John
Design and Synthesis of Fibroblast MULTIVALENT Drugs and Imaging Agents
2019-LOW-68745
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Low, Philip Stewart
New Method for Synthesizing HSN608 Anticancer Agent, HSN608s
2020-THOM-69095
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Thompson, David Harley
Deterministic Culturing of Single Cells in 3D
2020-SAVR-69076
  1. Biotechnology
  2. Materials and Manufacturing
Savran, Cagri Abdullah
Novel Vaccine Formulations for Mycobacterium Tuberculosis
2019-MITT-68665
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Mittal, Suresh K
Inhibitors of Lymphoid-Specific Tyrosine Phosphatase for Autoimmune Diseases and Cancer Immunotherapies
2020-ZHAN-68996
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Zhang, Zhong-Yin
Assessing In Vivo Efficacy of Drug Therapeutics by Monitoring Proteins from Extracellular Vesicles
2020-TAO-69103
  1. Biotechnology
  2. Pharmaceuticals
Tao, Weiguo Andy
Custom G4 Microarrays Can Determine a Large-Scale Ligand Binding Selectivity
2020-YANG-69054
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Yang, Danzhou
Novel inhalation formulations of polymyxins
2020-ZHOU-68990
  1. Pharmaceuticals
Zhou, Qi
High-throughput Label-free Enzymatic Bioassays using Automated DESI-MS
2020-COOK-69031
  1. Biotechnology
  2. Chemistry and Chemical Analysis
Cooks, Robert Graham
New Drug Candidate for Methicillin-Resistant Staphylococcus Aureus Bacterial Infection and Other Drug Resistant Bacteria
2020-RAMA-68859
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Ramachandran, Padinjaremadhom V
A Lab-on-Chip Platform for Measuring Real-time Nondestructive Extracellular Matrix Stiffness
2020-RAHI-68964
  1. Biomedical Engineering
  2. Pharmaceuticals
Rahimi, Rahim
Targeting T Cells in Tumor Microenvironments through Immunotherapy
2019-LOW-68726
  1. Pharmaceuticals
  2. Medical/Health
Low, Philip Stewart
High Throughput Cancer Treatment Screening with Magnetic Actuation Platform
2019-LEE-68700
  1. Biomedical Engineering
  2. Biotechnology
Lee, Hyowon
Fibroblast-targeted Drugs and Imaging for Improved Internalization and Retention
2019-LOW-68689
  1. Chemistry and Chemical Analysis
Low, Philip Stewart
Human Monoclonal Folate Receptor Beta Antibody
65627
  1. Biotechnology
  2. Medical/Health
Low, Philip Stewart
Nanoparticle Chemotherapeutic Delivery System that Aids in Development of Antitumor Immunity
2020-YEO-68760
  1. Pharmaceuticals
Yeo, Yoon
Antimicrobial Peptides Targeting Intracellular Bacteria
2019-CHMI-68405
  1. Chemistry and Chemical Analysis
Chmielewski, Jean Anne
Peptide Antibiotics Targeting Intracellular Pathogens
2014-CHMI-66831
  1. Pharmaceuticals
Chmielewski, Jean Anne
Small Molecule Proteasome Stimulators of Proteasome for Protein Degradation to Treat Alzheimer's and Parkinson's Diseases
2020-TRAD-68744
  1. Pharmaceuticals
  2. Biotechnology
Trader, Darci Jones
Faster and More Controlled RF Heating for Lyophilization Based on Statistical Electromagnetics
2019-PERO-68657
  1. Pharmaceuticals
  2. Biotechnology
Peroulis, Dimitrios
Potent, Selective Inhibitor of an Emerging Therapeutic Target for Cancer
2019-KRUS-68554
  1. Pharmaceuticals
Krusemark, Casey John
Single Step Method for Heterocycle Synthesis
2018-DAI-68010
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Dai, Mingji
In vitro Model for Testing Efficacy and Neurotoxicity of Neurotherapeutic
2020-KNIP-68758
  1. Biotechnology
  2. Pharmaceuticals
Knipp, Gregory Thomas
Novel Adenylyl Cyclase 1 Inhibitors for Chronic Pain and Opioid Dependence
2017-WATT-67991
  1. Pharmaceuticals
Watts, Val Joseph
Selective Antibiotics for Highly Resistant Enterococcus
2019-FLAH-68419
  1. Pharmaceuticals
Flaherty, Daniel P
Open Gradient Exposure Platform for Cell Culture
2017-LELI-67828
  1. Biotechnology
  2. Chemistry and Chemical Analysis
Lelievre, Sophie Andree
Selective Ubiquitin Specific Protease Inhibitors for Treatment of Multiple Myeloma and Other Cancers
2017-PEPE-67704
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Pepe, Antonella
Adenoviral Vector-Based Influenza Vaccine
64187
  1. Pharmaceuticals
Mittal, Suresh K
Novel Immunocompetent Breast Cancer Mouse Model
63133
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Mittal, Suresh K
Potent HIV Protease Inhibitor Against HIV/AIDS
2017-GHOS-67663
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Ghosh, Arun K
Completely Continuous Plug Flow Crystallization Process of Pharmaceutical Production
2016-KOSW-67539
  1. Pharmaceuticals
  2. Chemical Engineering
Nagy, Zoltan Kalman
Direct Contact Blood Brain Barrier Triculture
2015-KNIP-67191
  1. Pharmaceuticals
  2. Biotechnology
Knipp, Gregory Thomas
Library of Broad-Spectrum Coronavirus Therapeutics
2016-STJO-67409
  1. Pharmaceuticals
Mesecar, Andrew D
Novel Aryl Isonitrile Antimicrobials Active Against Clinically Important Bacterial Strains
2015-DAI-67104
  1. Pharmaceuticals
  2. Medical/Health
Dai, Mingji
Peptoid Cancer Drugs Targeting PCNA Designed via a Novel in Silico/In Vitro Pipeline
2016-DAVI-67362
  1. Pharmaceuticals
  2. Medical/Health
Davisson, Vincent Jo
Automating Mouse Behavioral Measures
65341
  1. Veterinary
  2. Biotechnology
Garner, Joseph
PatchSurfer: Software for Exploring Protein-Ligand Interactions
2015-KIHA-67111
  1. Biotechnology
  2. Computer Technology
Kihara, Daisuke
Inexpensive Crystallinity Detection for Pharmaceuticals and Other Formulations
2016-SIMP-67304
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Simpson, Garth J
Vinyl Ether Lipids with Cleavable Hydrophilic Headgroups Target Cell Cytoplasm with More Stability and Efficiency
99046
  1. Pharmaceuticals
  2. Food and Nutrition
Thompson, David Harley
Compounds with Potential Use in Development of Medications for the Treatment of Multidrug Resistant HIV-1
2015-GHOS-67161
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Ghosh, Arun K
Dihydroquinazoline-Derived Inhibitors for Alzheimer's Disease Treatment
65219
  1. Pharmaceuticals
  2. Medical/Health
Ghosh, Arun K
Precise Method to Lower Detection Limits of Nucleation Onset Using Raman and XRD
2015-SIMP-66994
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Simpson, Garth J
Microfluid Platform to Screen Cancer Drug for Delivery
66164
  1. Biomedical Engineering
  2. Pharmaceuticals
Park, Kinam
Affinity Stabilization of Protein Drugs
65558
  1. Biotechnology
  2. Pharmaceuticals
Topp, Elizabeth Murphy
Chemical Classification with Digital Compressive Detection
2013-BUZZ-66378
  1. Chemistry and Chemical Analysis
  2. Biotechnology
Buzzard, Gregery T
Potent Protease Inhibitors Against HIV
2014-GHOS-66624
  1. Pharmaceuticals
  2. Chemistry and Chemical Analysis
Ghosh, Arun K
Neuropathic and Inflammatory Pain Therapeutics Targeting Adenylyl Cyclase
2015-DAI-67035
  1. Pharmaceuticals
Dai, Mingji
Method for Detection of Transiently Interacting Proteins
66261
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Tao, Weiguo Andy
Tumor Detection/Treatment Model
2014-LELI-66695
  1. Biotechnology
Lelievre, Sophie Andree
Electromagnetic Drug Delivery Using Nanowires
2014-BORG-66652
  1. Biomedical Engineering
  2. Medical/Health
Borgens (DECEASED), Richard Ben
Chromeno[4,3,2-de]isoquinolines as Potent Dopamine Receptor Ligands
99031
  1. Pharmaceuticals
Nichols, David E
Synthesis of Novel Potent Nosocomial Antibiotics
66199
  1. Pharmaceuticals
  2. Medical/Health
Stauffacher, Cynthia
Dopamine Agonists
64153
  1. Pharmaceuticals
Nichols, David E
Topoisomerase I Inhibitors as Potential Anticancer Agents
65643
  1. Chemical Engineering
  2. Pharmaceuticals
Cushman, Mark S
Topoisomerase I Inhibitors Substituted with Carbohydrates
65707
  1. Biotechnology
  2. Pharmaceuticals
Cushman, Mark S
Tracking Cellular Internalization and Trafficking of Nanomaterials
66219
  1. Biotechnology
  2. Pharmaceuticals
Tao, Weiguo Andy
Synthesis and Applications of Trifluoroacetate
65561
  1. Chemistry and Chemical Analysis
  2. Pharmaceuticals
Colby, David Alan
Improved Retroviruses for Gene Therapy
61136
  1. Biotechnology
Sanders, David A
Quantification of Affinity-Selected Glycopeptides
64407
  1. Biotechnology
Regnier, Fred E
Internalization of Anticancer Cargo by Bladder Tumor Cells
65688
  1. Biotechnology
  2. Medical/Health
Aguilar, Ruben C