Enzyme-based Benzaldehyde Biosynthesis

Back to all technologies
Download as PDF
2022-DOUD-69562
Researchers at Purdue University have improved the efficiency of natural mechanisms for synthesis of benzaldehyde, an aromatic compound that serves as a pollinator attractant, flavor, and antifungal compound, among other uses. After vanillin, benzaldehyde is the second most important chemical for flavor and food industry. Conventional benzaldehyde synthesis is a two-step process and uses allergenic and pyrogenic compounds, and microbes, which is very time and energy consuming. The method developed at Purdue University for benzaldehyde biosynthesis uses specific enzymes, which was cloned by the researchers and enriched in plants to yield high levels of benzaldehyde production. The cloned enzymes have a distinct ratio of two subunits that must be maintained for optimal yield of benzaldehyde. This method of benzaldehyde production will better serve the needs of the dyes, plastic additives, cosmetics, fragrances, flavors, and antifungals industries.

Advantages
- Improved natural production mechanism
- Less time-intensive than industry-standard method

Applications
- Dyes
- Plastics additives
- Cosmetics
- Fragrances
- Flavors
- Antifungals

Technology Validation: The researchers identified ideal cross-species subunit combinations for maximum benzaldehyde synthesis.
Oct 25, 2021
Provisional-Gov. Funding
United States
(None)
(None)

(None)
PCT-Gov. Funding
WO
(None)
(None)
Purdue Office of Technology Commercialization
The Convergence Center
101 Foundry Drive, Suite 2500
West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org