Heterogeneous Hydroxyl-Directed Hydrogenation over a Pd-M Alloy Catalyst

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2021-LI-69317
Currently, there are no heterogeneous catalysts available for high yielding and stereoselective hydrogenation of hydroxyl-containing substrates. Researchers at Purdue University have developed a Pd-Cu nanoparticle heterogeneous catalyst for this application that demonstrates high conversion of up to 99% with diastereoselectivity as high 17:1 for the substrates examined. Because this is a supported catalyst, this also means that it can be easily recycled. Advances in this area have applications in pharmaceuticals and specialty chemicals.

Advantages:
- More cost effective than homogeneous alternatives
- Recyclable
- Heterogeneous

Applications:
- Pharmaceuticals
- Specialty chemicals

Technology Validation:
This technology has been validated through laboratory demonstration.
Jan 11, 2021
Provisional-Patent
United States
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Purdue Office of Technology Commercialization
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