Novel Agrobacterium Strains That Will Transiently Express But Not Integrate T-DNA

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2021-GELV-69237
Researchers at Purdue University have developed a new agrobacterium strain for genetic transformation in plants. Agrobacterium is used to append a region of transfer DNA (T-DNA) of tumor-induced (Ti-)plasmid to a plant, and T-DNA is processed from virD1 and virD2 virulence proteins to achieve genetic transformation. Traditionally, this process often leads to undesired genetic alterations. Purdue researchers have optimized a process for synthesizing a new agrobacterium strain to transfer T-DNA without integrating it into the plant genome.

Advantages:
-Gene Expression Without Genome Integration
-T-DNA Transfer to Plants

Potential Applications:
-Plant Genetics
-Agrobiosciences

Technology Validation: New mutations of virD2 have been studied

Recent Publication:
Dr. Stanton Gelvin's Project Webpage
https://www.bio.purdue.edu/People/faculty/gelvin/gelvinweb/completeproposal.html
Oct 6, 2021
Utility-Gov. Funding
United States
(None)
(None)

Oct 9, 2020
Provisional-Gov. Funding
United States
(None)
(None)
Purdue Office of Technology Commercialization
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Email: otcip@prf.org