Novel Approach to Induce Protection Against Respiratory Viruses

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2021-MITT-69166
Researchers at Purdue University have developed a new method for protecting against respiratory viruses by activating inherent immune response. The technique is virus-specific, promoting adaptation to specific viral strands such as influenza, SARS-CoV-2, respiratory syncytial virus (RSV), and others. This innovative method has been tested in vitro with human innate lymphoid cells (ILC) as well as in mice in vivo, exhibiting strong CD8 T-cell response. By increasing ILC response in the lungs of mice, a 60% survival rate was observed. Vaccination kits can be created using these results to protect against respiratory viruses.

Technology Validation:
-In vivo testing on mice
-In vitro testing on human ILC cells

Advantages:
-Rapid Immune Response
-Improved Survival Rate in Mice

Potential Applications:
-Virus Research
-Biotechnology
-Vaccinations
Aug 24, 2021
Utility-Gov. Funding
United States
(None)
(None)

Aug 27, 2020
Provisional-Gov. Funding
United States
(None)
(None)
Purdue Office of Technology Commercialization
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West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org