Novel Absorbance-Based Colorimetry from Droplets on Nonwetting Substrates

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Researchers at Purdue University have developed a novel sessile droplet method for highly efficient colorimetry on nonwetting substrates. Colorimetric reactions include mixing a coloring agent with a droplet of biologic sample quickly enough to cause a reaction while also producing a measure of sample concentration before these aqueous samples evaporate. The method created by Purdue University allows for diffusion two orders of magnitude higher than typical micro-titer plates. Natural buoyancy of droplets leads to induced convection, and can be coupled with surface heating for even faster mixing results – without dissipation. High throughput testing is now possible as the plates adapt instantly to droplet volume, and the fabrication of the overall colorimetry test setup is simplified.

-Adapts to volume of droplets
-Compatible with nonwetting surfaces
-Fast fabrication

Potential Applications:
-Laboratory Research
-Materials and Manufacturing
Aug 11, 2020
Utility Patent
United States
Dec 27, 2022

Aug 15, 2019
United States
Purdue Office of Technology Commercialization
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