Quantitative Sensor to Measure Cellular Metabolism

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Track Code	2019-TANT-68703
Categories	Biotechnology Chemistry and Chemical Analysis
Keywords	Biochemistry Biology Cancer Cancer Screening Cancer Therapy Cell Biology Cells Chemistry and Chemical Analysis Chemotherapy Fluorescense Fluorescent Dyes Gene & Cell Therapy Luminescence Measurements Metabolomics Molecular Biology Photons Probes Proteins Research Tools Sensors
Public Abstract	Researchers at Purdue University have developed a protein-based, genetically-encoded bioluminescent sensor that can report changes in intracellular ATP in live cells. This new sensor could be very useful for research purposes in cancer biology to measure cell health and chemotherapeutic drug efficacy. Advantages: -Measurement is independent of bioluminescence decay -Precisely quantifies cell health and metabolism Potential Applications: -High throughput drug discovery -Life animal imaging
People	Tantama, Mathew (Project leader) Min, Se-Hong
Intellectual Property	Application Date Jun 16, 2020 Type Utility-Gov. Funding Country of Filing United States Patent Number (None) Issue Date (None) Application Date Jun 18, 2019 Type Provisional-Patent Country of Filing United States Patent Number (None) Issue Date (None)
Contact OTC	Purdue Office of Technology Commercialization The Convergence Center 101 Foundry Drive, Suite 2500 West Lafayette, IN 47906 Phone: (765) 588-3475 Fax: (765) 463-3486 Email: otcip@prf.org