Instrumented Flexible Tissue Scaffolds Allowing for Real-time Monitoring of Engineered Tissues and Cells

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2019-LEE-68615
The continually growing engineered tissue market focusses on working to repair tissues or cells damaged by some of the world's most debilitating cancers and diseases. One major challenge in this field is monitoring and continuously testing performance of engineered tissues and cells used to replace damaged ones. Researchers at Purdue University have developed flexible tissue scaffolds that allow for real-time, long-term monitoring of engineered tissues and cells. This technology is a tissue scaffold with sensor arrays in a stackable design that can monitor electrophysiological activities of cells and tissues. Furthermore, the information provided by these scaffolds is made into 3D maps to track activity. Through usage of an ultra-buoyant scaffold design, the entire structure remains afloat on the cell culture medium, providing complete isolation of the electronic instrument from the wet conditions inside the body.

Advantages:
-Real-time, long-term monitoring
-3D mapping capabilities

Potential Applications:
-Engineered tissues and cells
-Drug screening
-Tissue development
May 26, 2020
Utility-Gov. Funding
United States
(None)
(None)

May 24, 2019
Provisional-Patent
United States
(None)
(None)
Purdue Office of Technology Commercialization
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Email: otcip@prf.org