Low Cost Synthesis of Lomustine Under Continuous Flow Conditions

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Track Code	2019-THOM-68395
Categories	Pharmaceuticals
Keywords	Cancer Therapy Drug Manufacturing Pharmaceuticals
Public Abstract	Researchers at Purdue University have developed a continuous manufacturing process for lomustine that has a short residence time and 63 percent yield. Major advantages of this process are that the total production cost for lomustine is lower, the product is higher quality, and the manufacturing operation is safer for production personnel. Advantages: -Control of purity -Continuous manufacturing Potential Applications: -Pharmaceutical manufacturing
People	Thompson, David H (Project leader) Cooks, Robert Graham Ferreira, Christina R Jaman, Zinia
Intellectual Property	Application Date Oct 16, 2019 Type Utility Patent Country of Filing United States Patent Number 10,941,111 Issue Date Mar 9, 2021 Application Date Oct 16, 2018 Type Provisional-Patent Country of Filing United States Patent Number (None) Issue Date (None)
Contact OTC	Purdue Office of Technology Commercialization The Convergence Center 101 Foundry Drive, Suite 2500 West Lafayette, IN 47906 Phone: (765) 588-3475 Fax: (765) 463-3486 Email: otcip@prf.org