Accurate Measurements of Nanoparticles in Fluidic Mediums

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Track Code	2019-SIMP-68376
Categories	Chemistry and Chemical Analysis Electrical Engineering
Keywords	Chemistry and Chemical Analysis Detection Nanoparticles Quantitative Phase Contrast Imaging
Public Abstract	Researchers at Purdue University have developed a noninvasive, label-free technique to quantify particle size distributions in suspensions, described as axially offset differential interference contrast correlation spectroscopy (ACID-CS). ACID-CS is more sensitive than traditional spectroscopy techniques such as dynamic light scattering, and unlike current technologies avoids time-dependent intensity fluctuations. ACID-CS enables accurate measurements of nanoparticles in fluidic mediums. The technique was demonstrated with silica beads of known size and will be useful for a myriad of scientific research applications, such as in protein nanocrystal suspensions. ACID-CS is adaptable for existing microscopes or can be readily implemented as its own apparatus. Advantages: -Fast -Accurate -Adaptable Potential Applications: -Research -Chemical Analysis
People	Simpson, Garth J (Project leader) Deng, Fengyuan Ding, Changqin Li, Chen
Intellectual Property	Application Date Nov 4, 2021 Type CIP-Gov. Funding Country of Filing United States Patent Number (None) Issue Date (None) Application Date May 24, 2021 Type Utility-Gov. Funding Country of Filing United States Patent Number (None) Issue Date (None) Application Date Jul 22, 2020 Type Provisional-Gov. Funding Country of Filing United States Patent Number (None) Issue Date (None)
Contact OTC	Purdue Office of Technology Commercialization The Convergence Center 101 Foundry Drive, Suite 2500 West Lafayette, IN 47906 Phone: (765) 588-3475 Fax: (765) 463-3486 Email: otcip@prf.org