Accurate Measurements of Nanoparticles in Fluidic Mediums

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Researchers at Purdue University have developed a noninvasive, label-free technique to quantify particle size distributions in suspensions, described as axially offset differential interference contrast correlation spectroscopy (ACID-CS). ACID-CS is more sensitive than traditional spectroscopy techniques such as dynamic light scattering, and unlike current technologies avoids time-dependent intensity fluctuations. ACID-CS enables accurate measurements of nanoparticles in fluidic mediums. The technique was demonstrated with silica beads of known size and will be useful for a myriad of scientific research applications, such as in protein nanocrystal suspensions. ACID-CS is adaptable for existing microscopes or can be readily implemented as its own apparatus.


Potential Applications:
-Chemical Analysis
Nov 4, 2021
CIP-Gov. Funding
United States

May 24, 2021
Utility-Gov. Funding
United States

Jul 22, 2020
Provisional-Gov. Funding
United States
Purdue Office of Technology Commercialization
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