Accurate Measurements of Nanoparticles in Fluidic Mediums

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2019-SIMP-68376
Researchers at Purdue University have developed a noninvasive, label-free technique to quantify particle size distributions in suspensions, described as axially offset differential interference contrast correlation spectroscopy (ACID-CS). ACID-CS is more sensitive than traditional spectroscopy techniques such as dynamic light scattering, and unlike current technologies avoids time-dependent intensity fluctuations. ACID-CS enables accurate measurements of nanoparticles in fluidic mediums. The technique was demonstrated with silica beads of known size and will be useful for a myriad of scientific research applications, such as in protein nanocrystal suspensions. ACID-CS is adaptable for existing microscopes or can be readily implemented as its own apparatus.

Advantages:
-Fast
-Accurate
-Adaptable

Potential Applications:
-Research
-Chemical Analysis
Jul 22, 2020
Provisional-Gov. Funding
United States
(None)
(None)
Purdue Office of Technology Commercialization
1801 Newman Road
West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org