| 2018-IRAZ-68316 | |
| Glaucoma is caused when pressure increases within the eye due to a buildup of an aqueous fluid between the cornea and the lens. Surgical methods combined with pharmaceuticals are utilized to treat glaucoma by lowering intraocular pressure (IOP). For example, methods such as trabeculectomy utilize a surgical procedure to make a small hole in the eye wall (sclera), which enables the aqueous humor to drain to a reservoir and lowers the IOP. Unfortunately, these methods do not offer a permanent solution for glaucoma patients as the drainage hole that is created may close over time. Researchers at Purdue University have developed an implantable filter-filled micro screw that, when surgically implanted into an eye, creates an interface between the anterior chamber and the external environment. This interface allows for aqueous humor to escape, decreases IOP, and treats the cause of glaucoma. This technology ensures that the surgically-opened interfaces will not open over time and prevents viruses and bacteria from entering the eye. Related Publication: Semi-permanent transcorneal filter support and in vivo surgical implantation technique for open-angle glaucoma treatment. Biomedical Microdevices, Vol. 21, Iss. 4. https://doi.org/10.1007/s10544-019-0440-7 Technology Validation: In testing on rabbit cadavers, saline injected into the anterior chamber of the eye successfully diffused through the implanted transcorneal duct, and IOP dropped. Advantages: - Decreases intraocular pressure - Keeps surgical incisions open over time - Prevents viruses and bacteria from entering eye Applications: - Glaucoma treatment - Other ophthalmic disorders |
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