Evaluate Glucose Concentrations Using an Automated & Selective Condenser for Collection of Exhaled Breath Condensate

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While self-monitoring of blood glucose is critical to properly controlling diabetes, 67% of patients fail to monitor their glucose levels due to the inconvenience of collecting finger-prick blood samples. Exhaled breath condensate (EBC) is a promising non-invasive sample for glucose monitoring purposes due to its highly controlled physiological regulation. However, this may reduce reliability because the concentration of glucose is diluted by additional water vapor and the inclusion of anatomical dead space air, causing a wide range of reported EBC glucose concentrations. By selectively collecting only exhaled breath that has been exchanged with lung fluid, it is anticipated that a greater fraction of glucose can be collected in the condensate.

Researchers at Purdue University have developed an automated and selective exhaled breath condenser for glucose monitoring. This is the first condenser of its kind to actually separate and exclude dead space air from lung fluid-exchanged air. The condensate collected from this device provides a robust sample for evaluating glucose concentrations without variable dilution factors from dead space condensate that could impact the reliability of the sample.

-Separates/excludes dead space air from lung fluid-exchanged air
-Provides robust sample for glucose concentration evaluation
-Improves reliability of glucose samples

Potential Applications:
-Glucose monitoring
-Glycemic control
-Diabetes treatment
Jul 2, 2018
United States
Purdue Office of Technology Commercialization
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