New Solid State Forms of Thiamine

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Thiamine, or vitamin B1, is widely added to foods and to vitamin tablets. Two solid state forms are currently used commercially: thiamine chloride hydrochloride and thiamine mononitrate. The former is quite hygroscopic and is typically used in liquid formulations. The latter form is less hygroscopic, so is used in food powders. However, there is a public perception that nitrates are bad; hence, there is a potential market for alternative solid state forms of thiamine.

Researchers at Purdue University have developed new solid state forms of thiamine through synthesis. These new forms are potentially less hygroscopic and are formed with more acceptable counterions. These thiamine solids help those in the food and nutraceutical industry who want to fortify foods and produce vitamin tablets. By adding thiamin forms that are chemically stable and acceptable to consumers, customers will be able to purchase products with better stability, longer shelf life, and will be able to consume more natural compounds unlike thiamine mononitrate or thiamine chloride hydrochloride.

-Better stability
-Reduce degradation
-More natural compounds

Potential Applications:
-Food fortification
-Vitamin tablets
May 28, 2019
Utility Patent
United States
Jul 21, 2020

Jun 5, 2018
United States
Purdue Office of Technology Commercialization
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