Optical Detection of Pathogen Interaction with Immortal Cell Line

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2018-LADI-68265
Finding biological pathogens requires recovery, concentration, and interrogation of small numbers of pathogenic bacteria. Current technologies face practical limitations, particularly in rapidly determining phenotypes of small numbers of isolated microorganisms. Conventional methods like polymerase chain reaction (PCR) and genomic technologies, enrichment, and molecular recognition require several limitations and sometimes do not offer solid results. These approaches do not enable the rapid detection of unknown pathogens.

Researchers at Purdue University have developed a method to rapidly detect the presence of unknown pathogens using an immortal cell line as a sensitive detector. This method is better than conventional methods because it is more sensitive, rapid, and is able to detect unknown pathogenic bacteria. The method can also be used to detect food pathogens such as Listeria and Salmonella.

Advantages:
-Detects unknown pathogenic bacteria
-Sensitive
-Rapid

Potential Applications:
-Food safety
-Biosecurity
Jun 7, 2019
Utility Patent
United States
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Jun 8, 2018
Provisional-Patent
United States
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Purdue Office of Technology Commercialization
1801 Newman Road
West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org