Portable Diagnostic Tool for Blast Injury and Other Traumatic Brain Injuries

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2017-SHI-67785
Blast injury, concussions, and other traumatic brain injuries display widespread damage, which makes diagnosis difficult and challenging to measure without expensive, bulky technologies that are not available outside of medical or research settings. Even in advanced clinical settings, current technology does not reliably detect mild head injuries, which are the most common. There is a lack of objective diagnostics indicative of multi-region brain injury for use in a variety of field conditions and for persons with limited training such as in military field operations, sports sidelines, ambulances, and emergency rooms. There is a need for a sensitive, objective, portable diagnostic tool that requires minimal training for use.

Researchers at Purdue University have developed a simple, portable, just press and go, rapid diagnostic tool that is easily deployable in a variety of settings and does not require specialized training. This device seamlessly integrates and administers a unique, configurable array of auditory stimuli that provide region-specific details regarding brain injury in an objective, quantifiable, and longitudinally monitored manner, which determines if the brain is injured and the extent and location of the brain injury. This diagnostic tool provides correlated information regarding damage to auditory and neighboring non-auditory structures in the brainstem, thalamus, and cortex, among other regions. This technology allows for rapid assessment using neurological functional metrics, as opposed to measurements of applied force to the head, anatomical indicators, or other non-validated tools, which have not proven reliable.

Advantages:
-Simple, portable, and easily deployable
-Does not require specialized training
-Easy to use
-In field use, e.g. military, sporting events, ambulances, emergency rooms
-Rapid assessment using neurological functional metrics

Potential Applications:
-Brain trauma analysis
-Auditory testing
-In field testing

Related Publications:
Riyi Shi, et al. Differences in post-injury auditory system pathophysiology after mild blast and non-blast acute acoustic trauma. Journal of Neurophysiology March 8, 2017. DOI: 10.1152/jn.00710.2016
Mar 16, 2018
Utility Patent
United States
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Mar 17, 2017
Provisional-Patent
United States
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Purdue Office of Technology Commercialization
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Email: otcip@prf.org