Synthetic Lung Surfactant for Respiratory Distress Syndrome

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2016-WON-67605
Respiratory distress syndrome (RDS) causes nearly 40 percent of premature infant deaths worldwide. A lack of natural surfactant in their under-developed lungs is the initial cause of RDS. Treatment is not readily available for RDS in developing countries because conventional surfactant replacement therapy uses animal-derived surfactants that are costly to produce, must be carefully stored, and require highly trained practitioners to perform a sophisticated delivery procedure.

Researchers from Purdue University have developed a synthetic polymer-based surfactant to treat RDS by supplementing the premature infant's naturally produced surfactants. The synthetic lung surfactant, proven effective by in vitro measurements using a lung-mimetic device, will be less expensive to produce and store and will not require delivery by skilled physicians. This simple, cost effective surfactant is a promising treatment to decrease the mortality rate of premature infants worldwide.

Advantages:
-Less costly to produce and store
-Less variation in production versus current animal-derived surfactant
-Treatment option for developing countries

Potential Applications:
-Respiratory distress syndrome
Feb 21, 2019
NATL-Patent
European Patent
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Feb 8, 2019
NATL-Patent
Japan
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Jan 26, 2018
CIP-Patent
United States
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Aug 11, 2017
PCT-Patent
WO
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Aug 11, 2017
NATL-Patent
Canada
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Aug 12, 2016
Provisional-Patent
United States
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Purdue Office of Technology Commercialization
1801 Newman Road
West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org