Trapping and Sensing Biomolecules and Nanoparticles

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2016-NNAN-67309
Current processes for trapping nanoparticles in an aperture are slow, even in top of the line systems. For instance, plasmonic aperture optical tweezers diffuse particles to an aperture trap via Brownian motion, which is a slow process that can take hours depending on the solution being diffused. This transportation system is a limitation of nano-optical tweezers in trapping the particles. In addition, accurate placement of particles in the hotspots of the aperture is also a problem. The placement of particles, such as quantum emitters, can affect their energy emission and hotspots of the aperture increase emission efficiency, allowing for certain readings that could be technologically relevant.

Researchers at Purdue University have developed a new method that could help solve the nanoparticle diffusion time issue as well as stabilize nano-objects in the hotspot of the aperture. Using light, a long range flow is induced that captures nanoparticles in a solution and delivers them to the aperture trap. This technique operates on a subsecond scale, beating the time limits of previous processes. In order to immobilize nano-objects on a hotspot of the aperture, researchers applied a DC or low frequency AC field, which essentially traps the nano-object on the hotspot. This is especially important for the aforementioned quantum emitters, as they interact positively with the hotspots and allow for more revealing information on quantum technology to be ascertained.

Advantages:
-Trapping mechanism operates on a subsecond time frame
-Improved hotspot targeting method
-Can be used for biomolecules and nanoparticles

Potential applications:
-Quantum technology
-Biology
Mar 31, 2017
Utility Patent
United States
10,180,383
Jan 15, 2019

Jan 15, 2019
DIV-Patent
United States
(None)
(None)

Mar 31, 2016
Provisional-Patent
United States
(None)
(None)
Purdue Office of Technology Commercialization
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