2014-COOK-66769 | |
Mass spectrometry is a critical tool that contributes to public health and safety, as well as a multitude of research endeavors, by identifying molecules as diverse as pesticides, toxins, drugs, and biomarkers implicated in human health. Ionization of sample molecules is critical to effective chemical analysis by mass spectrometry. Current ionization technologies often require large, highly sophisticated hardware. In addition, spectra may be compromised by ionization methods that create a variety of ions including fragmented molecules. Researchers at Purdue University, in collaboration with Professor N. Pradeep at the Indian Institute of Technology, Madras, have developed a method of ionization via a carbon nanotube impregnated surface that provides significant advantages to current methods. Samples may be collected by simply wiping the surface across the sample. Ionization is induced by a very small electrical potential. The resulting ionization is gentle on the sample, producing single ion species with no fragment ions. This method has been used to effectively identify pesticides, antibiotics, and amino acids. The small size, simplicity, and effective ionization of this method could easily be incorporated into new spectrometers more suited to portable use. Advantages: -Approximately 1,000 times lower voltage necessary compared to similar ionization methods -Gentle to samples, resulting in less complex spectra -Small, simple, inexpensive design Potential Applications: -Mass spectrometry -Chemical analysis/engineering |
|
|
|
Jan 2, 2020
CON-Gov. Funding
United States
10,991,564
Apr 27, 2021
Aug 23, 2019
DIV-Patent
Japan
6749459
Aug 13, 2020
Jul 19, 2019
CON-Patent
United States
10,559,455
Feb 11, 2020
Dec 22, 2014
EP-Patent
United Kingdom
3089811
Nov 6, 2019
Dec 22, 2014
NATL-Patent
Japan
6,577,950
Aug 30, 2019
Jun 14, 2016
NATL-Patent
United States
10,395,913
Aug 27, 2019
Sep 16, 2021
DIV-Gov. Funding
Japan
(None)
(None)
Sep 5, 2019
DIV-Patent
China
(None)
(None)
Aug 26, 2016
NATL-Patent
European Patent
(None)
(None)
Aug 26, 2016
NATL-Patent
China
(None)
(None)
Dec 22, 2014
PCT-Patent
WO
(None)
(None)
Dec 22, 2014
DIV-Patent
Japan
(None)
(None)
Jan 13, 2014
Provisional-Patent
United States
(None)
(None)
Dec 28, 2013
Foreign, Non-PCT
India
(None)
(None)
(None)
DIV-Patent
Europe
(None)
(None)
|
|
Purdue Office of Technology Commercialization The Convergence Center 101 Foundry Drive, Suite 2500 West Lafayette, IN 47906 Phone: (765) 588-3475 Fax: (765) 463-3486 Email: otcip@prf.org |