Detection of Food Pathogens

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In the U.S. alone, manufacturers spend $2.9 billion each year on food safety tests. Despite significant advances in food safety technologies, foodborne illnesses are more prevalent than ever. The Centers for Disease Control and Prevention (CDC) estimates each year about 48 million Americans are affected by foodborne illness, 128,000 are hospitalized, and 3,000 die. The detection of pathogens to prevent foodborne illness must be improved. There is an urgent demand for sensitive, rapid, cost-effective, widely translatable technologies to immobilize active bacteriophages that lead to foodborne illness.

Purdue University researchers have developed a biochip that detects pathogens in foods in real time and a method for using and maintaining the device. Cells are first concentrated. Then, the device can be put in the cell recovery mode to collect the retentate. The researchers developed a novel method for collecting the retentate so that the microbes can be analyzed. Accompanying software controls the unit's operation and allows for simultaneous filtration and cell recovery. The researchers have also developed a method for cleaning and sterilizing the instrument to allow reuse and address membrane fouling, which is the build-up of lipids, proteins, and other particles that block the membrane so fluid cannot flow through. Both developments will reduce costs associated with pathogen detection by extending the life of the equipment.

Advantages:
-Detects pathogens in real time
-Solves membrane fouling
-Extends equipment life
-Reduced costs

Potential Applications:
-Food Industry
-Food Safety
Mar 28, 2013
NATL-Patent
European Patent
2831577
Aug 8, 2018

Mar 28, 2013
EP-Patent
France
2831577
Aug 8, 2018

Mar 28, 2013
EP-Patent
United Kingdom
2831577
Aug 8, 2018

Mar 28, 2013
EP-Patent
Germany
602013041686.9
Jul 31, 2018

Sep 26, 2014
NATL-Patent
United States
9,651,551
May 16, 2017

Apr 12, 2017
CON-Patent
United States
(None)
(None)

Mar 28, 2013
PCT-Patent
WO
(None)
(None)

Mar 28, 2013
NATL-Patent
Canada
(None)
(None)

Nov 29, 2012
Provisional-Patent
United States
(None)
(None)

Mar 28, 2012
Provisional-Patent
United States
(None)
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Purdue Office of Technology Commercialization
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