| 65914 | |
| Desorption Electrospray Ionization (DESI) is a recently developed ambient ionization technique that can be used in mass spectroscopy (MS) for ambient chemical and biological analysis. DESI is capable of generating ions of analytes in raw samples with no separation and minimal sample preparation. DESI has been applied for tissue imaging, but only in biopsied samples. Researchers at Purdue have developed an ambient DESI probe with the potential to be deployed via catheter for in vivo sampling of biological samples. This probe is directly connected to the mass spectrometer via a length of tube, and the additional length of the tube has been shown to encourage desolvation of droplets and generation of ions for MS analysis. By using water instead of solvent-containing solutions, this device is capable of safely sampling biological surfaces. Advantages: -In vivo sampling -Non-hazardous sampling of biological surfaces Potential Applications: -Chemical Analysis |
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May 25, 2018
CON-Patent
United States
10,213,143
Feb 26, 2019
Jun 8, 2017
CON-Patent
United States
10,004,440
Jun 26, 2018
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CON-Patent
United States
9,700,251
Jul 11, 2017
Apr 16, 2015
CON-Patent
United States
9,538,945
Jan 10, 2017
Jun 1, 2012
Utility Patent
United States
9,024,254
May 5, 2015
Jan 15, 2019
CON-Patent
United States
(None)
(None)
Jun 3, 2011
Provisional-Patent
United States
(None)
(None)
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Purdue Office of Technology Commercialization 1801 Newman Road West Lafayette, IN 47906 Phone: (765) 588-3475 Fax: (765) 463-3486 Email: otcip@prf.org |