Radiofrequency Probe for Magnetic Resonance Imaging and Spectroscopy

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Currently, nanoscale imaging methods are limited due to the inability to investigate structural and chemical information at the single cell level. While there are imaging techniques that can be used for determining nanoscale structural information, these techniques are unsuitable for applications with living biological materials.

Researchers at Purdue University have developed a method for the investigation of structural and chemical information at the single cell level. This method uses a radiofrequency probe coupled with an atomic force microscopy cantilever for precise localization to areas of interest and magnetic resonance for determining nanoscale structural information. This technology couples the precision of atomic force microscopy with magnetic resonance imaging to allow for single cell imaging of living biological materials. This technology will allow researchers to gather nanoscale information on the surface and subsurface levels of individual cells.

Advantages:
-Offers precise localization to features/materials of interest
-Provides nanoscale structural information in addition to local spectroscopic information
-Suitable for investigation at the single cell level

Potential Applications:
-Medical/Healthcare
-Imaging
Nov 11, 2014
CIP-Patent
United States
9,500,671
Nov 22, 2016

Apr 10, 2014
NATL-Patent
United States
8,884,608
Nov 11, 2014

Oct 10, 2012
PCT-Patent
WO
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(None)

Oct 10, 2012
NATL-Patent
European Patent
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Oct 10, 2011
Provisional-Patent
United States
(None)
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Purdue Office of Technology Commercialization
1801 Newman Road
West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org