Discontinuous Atmospheric Pressure Interface

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Track Code	64870
Categories	Chemical Engineering Chemistry and Chemical Analysis
Keywords	Chemical Engineering Chemistry and Chemical Analysis Mass Spectrometry
Public Abstract	Mass spectrometry (MS) is commonly used in analytical laboratories that study physical, chemical, or biological properties of compounds. MS uses large vacuums to lower pressure in the chambers, which is necessary to maintain the integrity of the sample. The large vacuums limit the flexibility of adapting MS for portability and field use. Purdue University Researchers have developed discontinuous atmospheric pressure ionization (DAPI), which is a method of interfacing atmospheric pressure ion sources, including electrospray and desorption electrospray ionization sources, to mass spectrometers, for example miniature mass spectrometers, in which the ionized sample is discontinuously introduced into the mass spectrometer. Discontinuous introduction improves the match between the pumping capacity of the instrument and the volume of atmospheric pressure gas that contains the ionized sample. The reduced duty cycle of sample introduction is offset by operation of the mass spectrometer under higher performance conditions and by ion accumulation at atmospheric pressure. Advantages: -Allows for smaller mass spectrometers -Increases portability and field use Potential Applications: -Mass spectrometers -Field use of mass spectrometers
People	Ouyang, Zheng (Project leader) Cooks, Robert Graham Gao, Liang
Intellectual Property	Application Date May 30, 2008 Type DIV-Patent Country of Filing China Patent Number ZL20140195435.6 Issue Date May 24, 2017 Application Date May 30, 2008 Type NATL-Patent Country of Filing European Patent Patent Number 2160235 Issue Date Nov 30, 2016 Application Date May 30, 2008 Type EP-Patent Country of Filing United Kingdom Patent Number 2160235 Issue Date Nov 30, 2016 Application Date May 30, 2008 Type EP-Patent Country of Filing France Patent Number 2160235 Issue Date Nov 30, 2016 Application Date May 30, 2008 Type EP-Patent Country of Filing Germany Patent Number 2160235 Issue Date Nov 30, 2016 Application Date Sep 5, 2014 Type CON-Patent Country of Filing United States Patent Number 9,058,967 Issue Date Jun 16, 2015 Application Date Mar 27, 2014 Type CON-Patent Country of Filing United States Patent Number 8,853,627 Issue Date Oct 7, 2014 Application Date Oct 2, 2012 Type CON-Patent Country of Filing United States Patent Number 8,766,178 Issue Date Jul 1, 2014 Application Date May 30, 2008 Type NATL-Patent Country of Filing China Patent Number ZL 200880101096.3 Issue Date May 14, 2014 Application Date Nov 20, 2009 Type Utility Patent Country of Filing United States Patent Number 8,304,718 Issue Date Nov 6, 2012 Application Date Feb 25, 2011 Type PCT-Patent Country of Filing WO Patent Number (None) Issue Date (None) Application Date Feb 26, 2010 Type Provisional-Patent Country of Filing United States Patent Number (None) Issue Date (None) Application Date Oct 22, 2009 Type Provisional-Patent Country of Filing United States Patent Number (None) Issue Date (None) Application Date May 30, 2008 Type PCT-Patent Country of Filing WO Patent Number (None) Issue Date (None) Application Date May 30, 2008 Type NATL-Patent Country of Filing India Patent Number (None) Issue Date (None) Application Date Aug 3, 2007 Type Provisional-Patent Country of Filing United States Patent Number (None) Issue Date (None) Application Date Jun 1, 2007 Type Provisional-Patent Country of Filing United States Patent Number (None) Issue Date (None)
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