Microsensor Arrays for Bacterial Detection

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Concerns about biological warfare have piqued interest in sensitive detection of microorganisms such as viruses and bacteria. One method for detection of bacteria is to use the naturally occurring antibody-antigen chemistry to trap the bacteria onto a patterned substrate. Patterning the antibody into a microarray helps facilitate detection through a multitude of possible pattern recognition algorithms.

Purdue University researchers have developed a new method for multi-threat bacterial detection that is rapid, economical, and offers the potential for mass production. They have extended the microarray concept from the field of proteomics to biohazard detection. This method incorporates an immunological assay platform capable of reagent free, real-time antibody based detection of a wide variety of aqueous borne biocontaminants. The immunological complex formation can be sensed directly using an array of submicron sensing elements, and thereby, permitting multiple-threat detection capabilities. It is anticipated that upon insertion of a biochip into a handheld device, a positive identification of biohazard will occur in real time.

Advantages:
-Multiple-threat detection capability
-Positive biohazard identification in real time

Potential Applications:
-Biotechnology
-Biosensors
Apr 11, 2007
United States
7,867,754
Jan 11, 2011

Aug 1, 2003
United States
(None)
(None)

Aug 1, 2002
Provisional-Patent
United States
(None)
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Purdue Office of Technology Commercialization
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