Biofunctional Membrane for Detection of Pharmaceuticals and Toxins

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Biofunctional asymmetric membranes allow unidirectional transport of chemical and biological agents.

Researchers at Purdue University have developed novel approaches that allow the active transport structures on the biofunctional membranes to be oriented in large arrays and supported to provide directional transport and mechanical stability. This has been achieved using synthetic chemical and biological materials that are known to enhance stability. This approach will facilitate identification of promising pharmaceutical compounds, fingerprinting unknown environmental toxins based on membrane protein activity patterns, and rapid, high-throughput analysis of drug candidates for human multidrug resistance transporters and other membrane protein targets of disease.

Advantages:
-Automated
-Uses smaller quantities
-Faster
-Structure arrangement provides membrane with mechanical stability
-Facilitates identification of pharmaceutical compounds

Potential Applications:
-Medical/Healthcare
-Pharmaceuticals
-Biotechnology
-Drug Development
Apr 2, 2004
United States
7,374,944
May 20, 2008

Oct 3, 2002
PCT-Patent
WO
(None)
(None)

Oct 3, 2001
Provisional-Patent
United States
(None)
(None)
Purdue Office of Technology Commercialization
1801 Newman Road
West Lafayette, IN 47906

Phone: (765) 588-3475
Fax: (765) 463-3486
Email: otcip@prf.org